We have not done this in a while, but from time to time someone posts a poll to see how many miles folks have driven. Here is the most recent one I could find. There are also occasional threads such as this one that discuss the same topic.
I vaguely recall hearing stories about Karmas with 100K miles or more on them, usually from our advising experts such as @Harleyguy or @FiskerPhilly, but can't find a specific referernce right now (even the Search function has its limits).
A Karma, like any other car does not have an expiration date. The longevity depends on the quality of the individual components (that vary significantly from car to car) and how well they have been maintained and driven. Others may have more information on this, but I am not aware of anyone who got rid of their Karma because it wore out, and other than Karmas that have been flooded or damaged in major accidents, I have not heard of a Karma just dying and refusing attempts at resuscitation. Again, this is my personal information, which may be incomplete, but after 5 years, you would think that stories about cars that just refused to start one day after X miles, would be pretty well known.
Just for the record, My car is one of the original ones delivered in early 2012 and currently has 44K miles on it and seems to be <knocking on reclaimed wood> running just fine. I am on my original battery, third RDM, and second set of Traction Motors. But of course, YMMMV.